Ocular Findings in a Case of Hereditary Ochronosis.

THE literature apparently contains only four pathological examinations of the eye in hereditary ochronosis, and all of very recent date. The first two were carried out on biopsy material (Seitz, 1954; Rodenhiiuser, 1957) and the other two on the whole eye (Rones, 1960; Allen, O'Malley, and Straatsma, 1961). An ochronotic eye enucleated because of a mistaken diagnosis of malignant melanoma was examined only macroscopically as the discolouration of the sclera was thought to be due to formalin fixation (Skinsnes, 1948). The present report deals with a further example of this condition, and comprises the first histological account of an ochronotic globeremoved during the life of the patient.